The goal is to be responsible and innovative stewards of taxpayer dollars.
Over the last 25 years, $87 million has gone to Ohio businesses. Side-by-side they work to create technology that can work in space and in the lives of regular people.
Gynelle Steele is the program manager for Small Business Innovation Research at NASA Glenn Research Center.
She says practical application is something they always keep in mind.
"That our technology would have benefit not only to our science and space and aeronautics mission, but we could facilitate relationships that would build infusion of that technology into the commercial market," she said.
Two examples of that private public partnership are Goodyear in Akron and Zin Technologies in Cleveland.
At Goodyear, they've worked to create a tire made of springs that could navigate the rocky surface of the moon.
Plans to go back to the moon were axed as a part of President Barack Obama's NASA budget proposal but that doesn't mean the research at Goodyear will go to waste.
Steele says the tire will likely be used for military purposes. Using them on all-terrain vehicles because they won't puncture, they go faster and they are more energy efficient.
Another example is a device made by Zin Technologies, in Cleveland, that can monitor an astronaut's vital signs
Steele says the device will be able to go home with people who have trouble leaving their homes to go to the doctor.
The doctor can remotely monitor the patient and only have them come to the office if concerns are detected.
The device is in clinical trials right now in conjunction with the Cleveland Clinic. That will wrap up next month and, later this year, they will be tested in Europe.